He says, that he tried to no purpose to communicate the disease a second time to animals which had been fortunate enough to get cured.
That cows covered with the fresh skins stripped from dead cattle, victims to the distemper, did not contract it.
That infected clothes which had been worn by men who had served in hospitals where cattle were under treatment, having been laid on the backs of several beasts in sound health, were found to transmit the distemper in three cases out of six.
That the gases expelled from the intestines, received into a bladder ball, and let out under the noses of healthy cattle, have communicated the disease to them, after ten or fifteen days of latent incubation; and that the same gases being mixed with their drink, have also propagated the contagion.
That frictions, with the hands impregnated with virus, having been made over the skin, did not produce any ill effects.
That some oxen which had been designedly placed for a few hours among sick animals, have afterwards been seized with the distemper.
That a calf which had been placed in a stall containing some oxen grievously affected, but which calf had a basket beneath its nose filled with aromatic herbs, withstood the contagion.
That cowsheds which had been partially cleansed and fumigated, transmitted the disease to other cattle, even several months after they had been vacated.
Finally, he mentions the experiments of inoculation made by Lay and in England, but not understanding their aim and capacity, he adds, that inoculation does not seem to him of any use, since the inoculated animals all died. Yet he quotes the encouraging results obtained by Camper in Holland, who, out of 112 inoculated cattle, saved 41; and those of Koopman, who, out of 94, cured 45 by this very inoculation.
He reminds us that the cattle typhus is an abiding disease in Hungary and Russia, where the beasts having bad water to drink, can only be protected by a constant use of marine salt (sel gemme); but being deprived of this salt, when they go great distances to be sold, and being exposed to extreme fatigue and privations, the typhus then spreads among them. He likewise tells us that Hungary and Dalmatia, which used to supply the markets of Italy with butcher's meat, were obliged to give up sending any cattle there, the Italians having firmly refused to purchase the same at any price whatever.
As regards treatment, the advice which Vicq d'Azyr gives to agriculturists, is mostly borrowed from the authors who have written on the great epizootics of 1711, and 1745 to 1755. Thus, he advises them to give as drinks in the first stage, water whitened with meal and nitred; to purge the animals with linseed oil; even to make scarifications on the skin, and to keep up the suppuration with turpentine; to make the animals inhale six times a day vapours seasoned with vinegar; to wrap them over with woollen cloths; to bleed them once or twice; to administer to them, when diarrhœa shows itself, a beverage containing wormwood, quinine, and diascordium; to cut open the tumours containing pus or air, etc.
It is, as is seen, the same treatment as that quoted above; he guarantees its success, and supports his views by the authority of Van Swieten and Huxan.
Van Swieten, however, had somewhat modified the treatment, by the predominance which he allowed to acids; and this course seemed to him to be only reasonable with respect to animals whose sick humours contain an excess of alkali.
Vicq d'Azyr fixed his attention on the means of prevention, the most effectual of which, in his opinion, was to slaughter every animal which had either sickened, or had been exposed to the influence of the contagion; and as he insisted that the authorities had no measures to keep in this matter of public interest, he made it a principle that the government was bound to compensate the cattle proprietors whose animals had to be killed – the more so, said he, that the crafty husbandmen would never come forward and freely declare the invalidity of their cattle, unless some indemnity were held out to them, which they would look upon as a sort of equivalent for the benefits they had expected by cutting them up and selling them as the food of man.
The doctors of the period, scenting in Vicq d'Azyr a dangerous competitor, considered the advice of exterminating the diseased cattle as an ingenious means of curing them, and as the author's age and experience gave warrant for this satirical tone of discussion, the public joined them in laughing at him.
The epizootic typhus, if not so destructive, was at least as frequent in the early part of the nineteenth century, as it had been during the eighteenth. The armies during the wars of united Europe against the French Republic and Empire, found it constantly in their train. Nor could it be otherwise, the two leading causes of its prevalence being at hand. For on one hand there was the transit of large herds from the steppes of Hungary, and on the other the wretched hygienic conditions amidst which the cattle had to live in the campaigning armies.
Many books have been published of late years on the diseases of cattle, in France and Germany; and several distinguished English veterinary surgeons, especially Professor Simonds, have also devoted their attention to the same subject. In the second part of this work, we shall have occasion to refer to their labours.
In France, Renault, Delafond, d'Arboval, Gellé, whose works enjoy a deserved reputation, have discussed the subject of the origin of this disease.
Renault asserts that the disease has but one single focus, the steppes of Russia and Hungary. The epizootics of Asia, Africa, and South America are caused, he considers, by the importation of animals to those countries. It is thus that he explains the epizootia which, under the name of Delombodera, devastated the American Republics in 1832, and that which, in 1841, appeared in Egypt. Renault thinks that neither the long transit, nor the filthy state of the markets, nor the most wretched feeding, are sufficient to account for contagious typhus among cattle; that in addition to these causes, it still requires, in order to produce and generate it among animals, a predisposition, and a special aptitude, such as, hitherto at least, do not appear to have been witnessed except in the progeny of the steppes.
The other professors of his fraternity have submitted arguments to him, which to us seem very rational; and we will endeavour to do justice to them when we discuss the origin of the typhus which at this moment is afflicting England.
VI
These historical dissertations and speculations on the subject of the bovine epizootia certainly deserve to draw the attention of all who feel an interest in the malady; but how insignificant they are compared with the concluding facts which I have still to mention, before I at length address myself to the consideration of the epizootia which is now consuming our herds!
The indisputable fact that so terrible a distemper as this typhus had fixed itself permanently in Russia, and that it was causing incalculable losses to the lordly proprietors of the steppes, as well as to the government, roused them at last from their indifference. Then, indeed, they urged the veterinary doctors to adopt some energetic means to arrest the long duration of the scourge, and we must admit to their honour, that various experiments which were tried for the purpose of preventing the evil, have been crowned with complete success. Any one may ascertain the fact by referring to the Journal Magazin of Berlin, in which the learned Professor Jessen of Dorpat has explained the results of these important experiments.
The Russian veterinarians having observed that the oxen which had been cured of the typhus could mingle with impunity with the infected herds, conceived the idea of communicating the complaint to sound cattle by means of inoculation, and thereby to shield them from the contagion.
The first experiments in the inoculation of Tchouma or cattle typhus, were made in the year 1853, by order of the government, in the neighbourhood of Odessa, at the Heridin farm, by Professor Jessen.
The first inoculative attempts were very fatal; they caused the death of all the inoculated animals. But it was soon perceived that these grievous results, far from prejudicing the theory, really confirmed it; and that the virus, attenuated in its toxical properties, would prove as effectual as was expected. And truly, in 1854 and 1855, at the Dorpat establishment, the inoculations made with a better selected virus afforded results less disastrous. At Kozau they were still more satisfactory. In fine, passing from experiment to experiment, they arrived at the conclusion that it was necessary to inoculate several heads of cattle, the one after the other, without having recourse to any other virus than the first inoculated, so that they might thereby obtain virus of the 2nd, 3rd, 4th, 5th, and up to the 10th generation. The virus thus attenuated in its morbid effects answered at length every experiment, and oxen thus inoculated could mingle with impunity with diseased cattle.
At the veterinary establishment of Chalkoff they inoculated, during eight meetings, 1059 animals with virus of the 3rd generation, and the results were as satisfactory as could be wished for, only 60 animals having sunk under the effects of this preventive operation.
The inoculations made in 1857 and 1858 on an estate belonging to the Duchess Helena, at Karlowska, in the government of Pultawa, and conducted by the veterinarian Raussels, likewise afforded the most satisfactory results.
Professor Jessen thinks it certain, that beasts born of cows which have been afflicted with contagious typhus do not contract the disease. He maintains that Europe may be preserved from this frightful scourge, by taking care that no cattle be exported from the steppes of Russia save those which have had the distemper either naturally or by inoculation, and he is striving to propagate this opinion, and to render it practical, by having all the cattle inoculated, without exception.
It is deeply to be regretted that counsels so prudent have not been heeded in the 47 governments which, out of the 53 possessed by Russia, have generated the contagious typhus; for then it would not so frequently have effected its passage into the neighbouring states, and England most probably, would not now have to take up arms against its fatal extension.
VII
We here conclude that part of our labour which includes the history of this disease, and what we have been able to glean from those medical writers, and others, who have given us the results of their experience. It may have appeared somewhat protracted, but it has at least laid open to the student the antecedent investigations of our predecessors, under calamities of the same kind, but considerably more fatal than what has yet been witnessed in Western Europe during our time. We have disinterred and brought to light the forgotten works of conscientious and competent men. Like Brunelleschi, the architect, we have sought, not to invent a theory, but to recover a practice; and thus we have received the observations and precious facts, and finally the preventive treatment, of other men and other times, which had coped successfully against the cattle disease when its ravages were infinitely greater.
To resume, then: these inquiries (which we undertook without anticipating so rich a harvest) have proved, and made evident —
That the contagious typhus afflicting horned cattle, has spread its destructive principle over our globe ever since there have been animals living on its surface.
That from century to century, not to say from year to year, it has carried its terrors amidst nations and peoples.
That the remedial measures which had been taken and applied prior to the middle of the eighteenth century, were utterly powerless either to cure this disease or to prevent it.
That at that period appeared two English physicians, men of remarkable aptitude and penetration, one of whom, Malcolm Flemming, laid down in theory the bases of a preventive treatment; whilst the other, Peter Layard, applied this theory to practice, by inoculating sound and healthy animals with the morbid virus of the typhus, in order to protect them from the fatal effects of the contagion.
That this all-important progress in medical experience, has been absolutely forgotten; so much so, indeed, that the experiments of inoculation, tried in Russia only ten or twelve years ago with perfect success, do not seem to be connected by any link with those made in England a century before, and that the invasion of the so-called Cattle Plague in 1865 seemed to some men to have introduced a new scourge, which men were not armed and prepared to meet – which they were powerless to cure, or to stay in its progress.
These inquiries, then, have proved, we think, that we are not so helpless as we had imagined to resist the evil. But we cannot help feeling, that we have laid bare in this exposition some most distressing inferences concerning the human mind. For, in truth, can anything be more deplorable, than thus to see the civilized nations of Europe endure, from century to century, these reiterated outbreaks of cattle typhus, and to see likewise that no man of sufficient energy and independence has yet arisen to tell the truth fearlessly to the governments and peoples, however painful that truth may be, and to expose the futility of the measures hitherto employed to arrest the scourge?
And, on the other hand, is it not most afflicting to see discoveries of indisputable value buried out of view, submerged in public libraries, utterly unknown and forgotten, like their authors, to such a degree, that the distemper which they have made known in its entirety, and which is as old as the world itself, seems to us almost new in 1865?
God send, that these cruel trials and severe lessons which the past has bequeathed to us may teach us something for our benefit! May the irresistible might which is derived from the auspicious union of capital and intelligence supersede the vain and flimsy efforts of isolated energy! May the government, which lavishes hundreds of millions upon the destructive engines of war, devote some portion of its ample means to the study of hereditary infections and contagious diseases! For these fatal epidemics decimate men as well as cattle, and we may at least ward off from our children the desolating disease which at present afflicts ourselves.
We possess already every requisite means to protect ourselves from the formidable visitation of these diseases: we have science; we have the men who cultivate and teach it; we have the experience of the past added to our own. To-day, we are called upon to resist the baleful effects of cattle typhus; but another epizootia may come to-morrow, and strike our horses and our sheep – those domestic animals which constitute our most precious possession. The cholera hovers about us. If we do nothing, if we talk and debate instead of acting, these scourges will come upon us on a sudden, and find us quite as helpless as ever to resist their sway.
These palpable truths deserve to be further developed, and will be treated more copiously at the end of this book. They will constitute the complement of our work, necessarily written in haste, since the danger we had to expose was itself so urgent and alarming.
SECOND PART
This Part is divided, as already stated, into four chapters.
CHAPTER I
On Typhous Diseases in general, and the Typhus which affects the Ox in particular
By following the example of those authors who have described the contagious typhus of the ox, we might proceed at once to explain its symptoms, and go directly to our purpose; but, by taking this hasty course, we should expose ourselves to be imperfectly understood by the majority of our readers, and to leave certain doubts in the minds of physicians as to the nature of the disease and the propriety of its treatment.
All animals, including man himself, are born with a predisposition and liability to contract a certain number of contagious febrile diseases; they bear in a manner a certain number of physiological elements, which might be called latent germs, and which, under given conditions, become the leaven of these diseases. This must, indeed, be the case, since after these disorders have been once developed those who have been cured of them are not apt to contract them again, the morbid developments having destroyed that natural aptitude which had previously existed to undergo the morbid action of the contagious virus. These diseases are not numerous; they constitute a very distinct class, and the same laws, which regulate the phenomena in one of them are applicable to all the rest.
These diseases exhibit the following characteristics: 1st, a period of incubation, during which the whole economy, more particularly the blood and humours, experience very important changes and modifications; 2nd, a febrile state, which varies in its continuous or intermittent types, and in its intensity, according to the species of the animals, and which proceeds from the alteration of the blood; 3rd, a revulsion at once toxical and congestive towards the nervous centre, inducing stupor; 4th, a flux of mucus from the mouth and chest; 5th, a more intense, congestive, and inflammatory flux or discharge from the external or internal teguments – the skin or the mucous membrane of the digestive channels; 6th, a period of adynamia and dejection, with a tendency, in some cases, to a critical or salutary rejection of the morbid matter by the development of tumours or abscesses in the skin; 7th, they are at once infectious and contagious, epizootic or epidemic; that is to say, they are transmitted in different degrees by contact, by inoculation, and at a distance by the means of vitiated air; 8th, finally – and this is their leading characteristic —they are not subject to recurrence, each individual that has once been affected, losing in general all aptitude to contract the disease a second time.